The study will test:
Andrea Hansis-diarte
+1 (210) 617-5300
hansisdiarte@uthscsa.edu
Susan Kaiser
susan.kaiser@va.gov
Principal Investigator
Devjit Tripathy
Andrea Hansis-diarte
+1 (210) 617-5300
hansisdiarte@uthscsa.edu
Susan Kaiser
susan.kaiser@va.gov
Devjit Tripathy
(210) 567-6691
tripathy@uthscsa.edu
Arm | Description | Intervention |
---|---|---|
Healthy Volunteer Male | Healthy male currently on no testosterone treatment | This clamp technique is designed to obtain independent measures of insulin secretion and insulin sensitivity during the same test. In brief, 0.3g/kg body wt of a 20% glucose solution is given at time 0. Blood samples for the measurement of plasma glucose and serum insulin are obtained at -10, 0, 2, 4, 6, 8, 10, 20, 30, 40, 50, 60, 120, and 180 min. Other names:
|
MTF group | MTF transgender currently on estrogen treatment | GAHT, either estrogen or testosterone therapy will be withdrawn after the Botnia Clamp. This clamp technique is designed to obtain independent measures of insulin secretion and insulin sensitivity during the same test. In brief, 0.3g/kg body wt of a 20% glucose solution is given at time 0. Blood samples for the measurement of plasma glucose and serum insulin are obtained at -10, 0, 2, 4, 6, 8, 10, 20, 30, 40, 50, 60, 120, and 180 min. Other names:
|
Healthy Volunteer Female | Healthy female currently on no estrogen treatment | This clamp technique is designed to obtain independent measures of insulin secretion and insulin sensitivity during the same test. In brief, 0.3g/kg body wt of a 20% glucose solution is given at time 0. Blood samples for the measurement of plasma glucose and serum insulin are obtained at -10, 0, 2, 4, 6, 8, 10, 20, 30, 40, 50, 60, 120, and 180 min. Other names:
|
FTM group | FTM transgender group currently on testosterone treatment | GAHT, either estrogen or testosterone therapy will be withdrawn after the Botnia Clamp. This clamp technique is designed to obtain independent measures of insulin secretion and insulin sensitivity during the same test. In brief, 0.3g/kg body wt of a 20% glucose solution is given at time 0. Blood samples for the measurement of plasma glucose and serum insulin are obtained at -10, 0, 2, 4, 6, 8, 10, 20, 30, 40, 50, 60, 120, and 180 min. Other names:
|