PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Alice Conde
(210) 617-5190
condea@uthscsa.edu
Sara Espinoza
(210) 617-5197
espinozas2@uthscsa.edu
Sandra Idar
(210) 450-0568
idars@uthscsa.edu
Principal Investigator
Nicolas Musi
Alice Conde
(210) 617-5190
condea@uthscsa.edu
Tiffany Cortes
(210) 450-8998
cortest@uthscsa.edu
Sara Espinoza
(210) 617-5197
espinozas2@uthscsa.edu
Sandra Idar
(210) 450-0568
idars@uthscsa.edu
Nicolas Musi
(210) 562-6140
musi@uthscsa.edu
Arm | Description | Intervention |
---|---|---|
atorvastatin 40mg | 40mg atorvastatin po qd from consent to study end | To generate knowledge about the role of statins in older adults in whom risk/benefit for primary prevention is understudied, Other names:
|
Placebo | matching placebo po qd from consent to study end | To generate knowledge about the role of statins in older adults in whom risk/benefit for primary prevention is understudied, |