Lay Description

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists that has been shown to prolong survival. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with genetic changes or abnormalities (mutations) may benefit more from treatment which targets their tumor's particular genetic mutation, and may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas.


  • Child Health
  • Multiple Sites
IRB Number
NCT Number
Open to Enrollment


Eligible Ages
Between 12 Months and 21 Years
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

Exclusion Criteria

Study Design

Arm Groups

Study Contact

Virginia Diaz
(210) 562-9149

Jaclyn Hung
+1 (210) 450-5358

Anne-Marie Langevin
(210) 567-7460

Virginia Diaz
(210) 562-9149

Jaclyn Hung
+1 (210) 450-5358

Principal Investigator
Anne-Marie Langevin