Lay Description

The investigators propose a cluster randomized effectiveness trial comparing Cognitive Adaptation Training (CAT; a psychosocial treatment using environmental supports such as signs, alarms, pill containers, checklists, technology and the organization of belongings established in a person's home or work environment to bypass the cognitive and motivational difficulties associated with schizophrenia ) to existing community treatment (CT) for individuals with schizophrenia in 8 community mental health centers across multiple states including 400 participants. Mechanisms of action will be examined. Participants will be assessed at baseline and 6 and 12 months on measures of functional and community outcome, medication adherence, symptoms, habit formation and automaticity, cognition and motivation.


IRB Number
NCT Number
Open to Enrollment


Eligible Ages
Between 18 Years and 65 Years
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

  1. Males and females who have given informed consent.
  2. Between the ages of 18 and 65.
  3. Clinical Diagnosis of Schizophrenia, or Schizoaffective Disorder
  4. Able to provide evidence of a stable living environment (individual apartment, family home, board and care facility) within the last three months and no plans to move in the next year.
  5. Able to understand and complete rating scales and assessments.
  6. Agree to home visits
  7. Be able to have reimbursed home visits as part of treatment

Exclusion Criteria

  1. Alcohol or drug or dependence within the past 2 months.
  2. Currently being treated by an Assertive Community Treatment (ACT) team.
  3. History of assault within the past year or other conditions that in the judgement of the treatment team make home visits unsafe.

Study Design

Arm Groups

Study Contact

Feiyu Li

Dawn Velligan
(210) 567-5508

Feiyu Li

Principal Investigator
Dawn Velligan