Find-A-Study

Memory Improvement Through Nicotine Dosing (MIND) Study

Lay Description

The purpose of the study is to see if daily transdermal nicotine is able to produce a significant cognitive, clinical and functional improvement in participants with MCI. Neuronal nicotinic receptors have long been known to play a critical role in memory function in preclinical studies, with nicotine improving attention, learning, and memory function.

The study will enroll 300 participants for a 2 year period. Participants will be randomized (50:50) to either the transdermal nicotine, beginning at 7mg/day, and increasing to 21mg/day, or placebo skin patch.

Eligibility

Eligible Ages: Between 55 Years and 90 Years
Eligible Genders: All
Accepts Healthy Volunteers: No

Inclusion Criteria

Exclusion Criteria

Study Design

Arm Groups

Study Contact

Floyd Jones
+1 (210) 450-3158
jonesfa@uthscsa.edu

Amy Saklad
(210) 567-8229
saklada@uthscsa.edu

Sudha Seshadri
(210) 450-8437
Seshadri@uthscsa.edu