Volunteer Login Study Team Login

Print

Lay Description

Creatine is one of the most studied supplements with research demonstrating its efficacy in augmenting training adaptations such as improved strength and physical function in a variety of healthy and clinical populations. Given the additive effects of creatine and exercise improving muscle performance and lean body mass, it is not surprising that creatine is being explored as a cancer therapeutic to improve survivorship. However, the paucity of research in this area stems from the lack of awareness of the potential role of creatine supplementation in cancer survivors. Therefore, the purpose of this project is to test the hypothesis that creatine will accelerate adaptations associated with exercise in cancer survivors that are engaged in the Thrivewell Exercise Program.

Category

  • Cancers and Other Neoplasms
  • Cancer Survivors
IRB Number
20190610HU
NCT Number
NCT04207359
Open to Enrollment
Yes

Eligibility

Eligible Ages
18 - 75
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age 18-75 years of age
  • Recent (within 6 months) completion of chemotherapy
  • Willing to attend 3 clinic based exercise sessions per week
  • Able to take oral medications

Participant is willing and able to provide consent to participating in the study

Exclusion Criteria

  • Physical indications where performing exercise may be limited and/or contraindicated poorly-controlled hypertension (blood pressure > 160/95mmHg)
  • Current tobacco use (within 6 months)
  • Anabolic steroids
  • Pitting edema
  • Currently undergoing medical treatment for cancer (i.e. currently undergoing hormone therapy, chemotherapy or radiation therapy).
  • History of moderate-severe heart disease (New York Heart Classification greater than grade II) or pulmonary disease (dyspnea on exertion upon climbing one flight of stairs or less; abnormal breath sounds on auscultation).
  • Abnormal lab values for serum creatinine
  • Currently taking creatine supplements

Study Design

Study Contact

Regulatory Point of Contact
Amber Gallegos
(210) 606-2437
gallegosa4@uthscsa.edu

Regulatory Point of Contact
Darpan Patel
(210) 567-0362
pateld7@uthscsa.edu

Local Recruitment Point of Contact
Amber Gallegos
(210) 606-2437
gallegosa4@uthscsa.edu

Overall Recruitment Point of Contact
Angela Gonzalez

gonzaleza46@uthscsa.edu

Principal Investigator
Darpan Patel