Purpose

3 groups from background (general) population including Mexican ancestry will be studied: 1) individuals hospitalized with COVID-19, 2) Individuals (positive PCR) who recovered from mild COVID-19, and 3) COVID-19 negative (by PCR) seen in outpatient clinic or ER

Category

IRB Number
20220656HU
NCT Number
NCT05867017
Open to Enrollment
Yes
Sponsor
-



Study Contact

Andrea Hansis-diarte
+1 (210) 617-5300
hansisdiarte@uthscsa.edu

Marzieh Salehi
(210) 567-6691
salehi@uthscsa.edu

Nancy Yegge
(210) 450-8696
yeggen@uthscsa.edu

Principal Investigator
Ralph DeFronzo

Ralph DeFronzo
(210) 567-6691
defronzo@uthscsa.edu

Andrea Hansis-diarte
+1 (210) 617-5300
hansisdiarte@uthscsa.edu

Marzieh Salehi
(210) 567-6691
salehi@uthscsa.edu

Nancy Yegge
(210) 450-8696
yeggen@uthscsa.edu



Eligibility

Eligible Ages
18-75
Eligible Genders
all
Accepts Healthy Volunteers
No

Inclusion Criteria

    Body weight less than 350 lbs

Exclusion Criteria

    Diabetes prior to COVID infection; History of Myocardial infarction or stroke within 6 months or history of major organ system disease prior to COVID-19 infection.


Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Other
Condition
  • COVID-19
  • Diabete Mellitus

    • Arm Groups

    ArmDescriptionIntervention

    COVID-19 negative Group


    		COVID-19 negative (by PCR) and seen in outpatient clinics or ER during same time period as Groups I and II.
    • Other: Measure of physiologic parameters

      Participants will have hepatic muscle and adipose tissue insulin sensitivity tested


    Severe COVID-19 Group


    		Hospitalized with COVID-19 (PCR positive) and recovered
    • Other: Measure of physiologic parameters

      Participants will have hepatic muscle and adipose tissue insulin sensitivity tested


    Mild COVID-19 positive Group


    		COVID-19 positive (by PCR) who recovered from mild COVID-19 and were seen in outpatient clinics or ER with symptoms that did not justify hospitalization.
    • Other: Measure of physiologic parameters

      Participants will have hepatic muscle and adipose tissue insulin sensitivity tested