Lay Description

We are investigating the use of high-intensity interval training (HIIT) to improve participant’s ability to tolerate docetaxel chemotherapy treatments for metastatic prostate cancer.


  • Cancers and Other Neoplasms
  • Mens Health
  • Prostate Cancer
IRB Number
NCT Number registration not required
Open to Enrollment


Eligible Ages
Min 18 - No Max
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

  • Diagnosis of metastatic prostate cancer
  • Planning to receive docetaxel chemotherapy treatment
  • Have not started chemotherapy treatment.
  • Willing to commit to 3 in-person study visits per week over the course of the study
  • At least 4 weeks after from any major surgery

Exclusion Criteria

  • Uncontrolled high blood pressure (hypertension)
  • Diagnosis of small cell neuroendocrine prostate cancer
  • Receiving any other chemotherapy drug besides docetaxel
  • Heart attack, stroke, or transient ischemic attack in the last 6 months
  • Heart failure
  • Chest pain (angina)
  • Secondary cancer (may be eligible if second cancer is non-melanoma skin cancer or non-invasive bladder cancer)
  • Severe bone pain
  • Physical limitations that would prevent exercise participation
  • Already active (more than 1 hour per day of vigorous aerobic exercise or structured resistance exercise for 2 or more days per week)
  • Uncontrolled asthma

Study Design

Arm Groups

Study Contact

Regulatory Point of Contact
Crisann Moon
(210) 288-0488

Regulatory Point of Contact
Darpan Patel
(210) 567-0362

Local Recruitment Point of Contact
Crisann Moon
(210) 288-0488

Principal Investigator
Darpan Patel