Lay Description

A clinical trial to determine if Varoglutamstat (PQ912) is effective in slowing effects of Alzheimer's Disease


  • Behaviors and Mental Disorders
  • Dementia / Alzheimers
  • Aging and Geriatric
IRB Number
NCT Number
Open to Enrollment


Eligible Ages
50-89 inclusive
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

Diagnosed with Mild Cognitive Impairment due to AD or Mild probable AD. 

Have had an MRI w/in the Past Six Months

Have a study partner who has frequent interaction with the participant (3-4 times per week) and can accompany the participant to all visits.  

Exclusion Criteria

Have been diagnosed with a disease known to cause dementia including (but not limited to) Parkinson's Disease, Huntington disease, Lewy Body Disease, or AIDS. 

Have a mental illness judged to be not well controlled in the opinion of the PI. 

Medical Contraindications to undergoing an MRI or Lumbar Puncture. 

Have a medical condtion determined to be not well controlled on medication in the opinion of the PI.   

Study Design

Arm Groups

Study Contact

Floyd Jones
+1 (210) 450-3158

Sudha Seshadri
(210) 450-8437

Principal Investigator
Sudha Seshadri