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Lay Description

We are seeking adults with Down Syndrome without any signs or symptoms of dementia to gather information needed for the development of future clinical trials on Alzheimer’s Disease in the Down Syndrome population.  Individuals enrolled will undergo neuropsychological testing, imaging studies, and have blood and urine samples collected for clinical and genetic studies. 

Category

  • Aging and Geriatric
  • Dementia / Alzheimers
IRB Number
20220340HU
NCT Number
NCT04165109
Open to Enrollment
Not set

Eligibility

Eligible Ages
25-55
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

1) Mental age of 4 years or greater; 2) Have a reliable study partner (caregiver, sibling, parent etc.) who can accompany participant to visits and provide information about their medical symptoms and history; 3) Must be able to speak English or Spanish fluently ​​​​​​​

Exclusion Criteria

1) Unable or unwilling to undergo an MRI or PET scan; 2) If Female, pregnant, plan to become pregnant in the next 16-24 months, or currently breastfeeding, 3) Also participating in a clinical trial for an investigational product.      ​​​​​​​

Study Design

Arm Groups

Study Contact


Floyd Jones
+1 (210) 450-3158
jonesfa@uthscsa.edu

Floyd Jones
+1 (210) 450-3158
jonesfa@uthscsa.edu

Principal Investigator
Sarah Savoia