Lay Description

We are seeking adults with Down Syndrome without any signs or symptoms of dementia to gather information needed for the development of future clinical trials on Alzheimer’s Disease in the Down Syndrome population.  Individuals enrolled will undergo neuropsychological testing, imaging studies, and have blood and urine samples collected for clinical and genetic studies. 


  • Aging and Geriatric
  • Dementia / Alzheimers
IRB Number
NCT Number
Open to Enrollment
Not set


Eligible Ages
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

1) Mental age of 4 years or greater; 2) Have a reliable study partner (caregiver, sibling, parent etc.) who can accompany participant to visits and provide information about their medical symptoms and history; 3) Must be able to speak English or Spanish fluently ​​​​​​​

Exclusion Criteria

1) Unable or unwilling to undergo an MRI or PET scan; 2) If Female, pregnant, plan to become pregnant in the next 16-24 months, or currently breastfeeding, 3) Also participating in a clinical trial for an investigational product.      ​​​​​​​

Study Design

Arm Groups

Study Contact

Floyd Jones
+1 (210) 450-3158

Floyd Jones
+1 (210) 450-3158

Principal Investigator
Sarah Savoia