Purpose

This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

Category

IRB Number
20070394HU
NCT Number
NCT00898365
Open to Enrollment
Yes
Sponsor
Children's Oncology Group -



Study Contact

Jaclyn Hung
+1 (210) 450-5358
hungj@uthscsa.edu

Principal Investigator
Anne-Marie Langevin

Virginia Diaz
(210) 562-9149
diazvr@uthscsa.edu

Jaclyn Hung
+1 (210) 450-5358
hungj@uthscsa.edu



Eligibility

Eligible Ages
Under29 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

    Exclusion Criteria


      Study Design

      Study Type
      Observational
      Observational Model
      Case-Only
      Time Perspective
      Prospective
      Condition
    1. Adult Cystic Nephroma
    2. Anaplastic Kidney Wilms Tumor
    3. Angiolipoma
    4. Cellular Congenital Mesoblastic Nephroma
    5. Classic Congenital Mesoblastic Nephroma
    6. Clear Cell Sarcoma of the Kidney
    7. Congenital Mesoblastic Nephroma
    8. Cystic Partially Differentiated Kidney Nephroblastoma
    9. Diffuse Hyperplastic Perilobar Nephroblastomatosis
    10. Extrarenal Rhabdoid Tumor
    11. Kidney Medullary Carcinoma
    12. Kidney Neoplasm
    13. Kidney Oncocytoma
    14. Kidney Wilms Tumor
    15. Metanephric Adenofibroma
    16. Metanephric Adenoma
    17. Metanephric Stromal Tumor
    18. Metanephric Tumor
    19. Mixed Congenital Mesoblastic Nephroma
    20. Ossifying Renal Tumor of Infancy
    21. Papillary Renal Cell Carcinoma
    22. Renal Cell Carcinoma
    23. Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions
    24. Rhabdoid Tumor of the Kidney
    25. Wilms Tumor

      26. Arm Groups

      ArmDescriptionIntervention

      Ancillary-correlative (renal tumor classification, biology)

      		Tumor tissue, blood, and urine samples are collected for research studies, including immunohistochemistry. CT scans and MRIs are also performed. Loss of heterozygosity analyses (chromosome 1p and 16q) are performed by extraction of DNA. DNA polymorphisms are assayed by polymerase chain reaction using standard methodology. Leftover specimens are archived for future studies. (LOH and INI1 testing discontinued as of April 2014)
    26. Other: Laboratory Biomarker Analysis

      Correlative studies

    27. Other: Cytology Specimen Collection Procedure

      Correlative studies

      Other names:

      • Cytologic Sampling

      28.