Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Lay Description
The goal of this randomized, open labelled clinical trial is to examine the efficacy, durability, and mechanism of HbA1c reduction produced by the combination of pioglitazone plus tirzepatide versus metformin plus sitagliptin in recently diagnosed type 2 diabetes mellitus patients.
The main question[s] it aims to answer are:
How effective is the combination of pioglitazone plus tirzepatide in managing blood sugar levels in people with type 2 diabetes?
How does this combination compare to the use of metformin plus sitagliptin in controlling blood sugar levels?
Category
- Diabetes
- IRB Number
- STUDY00000139
- NCT Number
- NCT06246799
Eligibility
- Eligible Ages
- Eligible Genders
- Accepts Healthy Volunteers
Inclusion Criteria
Exclusion Criteria
Study Design
Arm Groups
Study Contact
Gozde Baskoy
210-358-7200
baskoy@uthscsa.edu
Andrea Hansis-Diarte
210-567-3208
hansisdiarte@uthscsa.edu
Andrea Hansis-Diarte
210-567-3208
hansisdiarte@uthscsa.edu
Principal Investigator
Muhammad Abdul-Ghani