Find-A-Study

EA 2185: Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs (CTMS# 23-0165)

Lay Description

The primary goal of this study is to compare the clinical effectiveness and associated resource utilization of the Fukuoka and AGA guidelines for pancreatic cyst surveillance.

Eligibility

Eligible Ages: 50-75
Eligible Genders: ALL
Accepts Healthy Volunteers

Inclusion Criteria

Patient must be ≥ 50 years and ≤ 75 years of age.
Patient must not have acute pancreatitis or a history of chronic pancreatitis.
Patient must have received a CT, MRI, or EUS within 6 months prior to randomization that revealed one or more ≥ 1 cm pancreatic cyst (s).
Patients of childbearing potential must not be known to be pregnant.
Patient must not have a prior diagnosis of pancreatic malignancy of any type.
Patient must not have a history of pancreatic resection.
Patients with only pancreatic lesions without malignant risk (pancreatic pseudocyst or classic serous cystic lesion) are not eligible.
Patient must not have a family history of pancreatic adenocarcinoma in one or more first-degree relatives(biological parents, full siblings or children).
Patient must not have pancreatic cyst morphology that would prompt immediate surgical consideration (enhancing mural nodule, solid ECOG-ACRIN EA2185 Cancer Research Group Version Date: May 25, 2023 18 component in cyst, pancreatic duct ≥10mm, cyst causing obstructive jaundice).
Patient must not have a comorbid illness that precludes EUS or pancreatic cyst resection.
Patient must not be currently participating in pancreatic cyst surveillance defined as organized, periodic up-to-date imaging directed towards the pancreatic cyst of interest.

Exclusion Criteria

Study Design

Arm Groups

Study Contact

Frances Crawford
210-450-5037
crawfordf1@uthscsa.edu

Myrna Montenegro
210-450-5954
montenegro@uthscsa.edu

Kathleen Rodriguez
210-450-1365
rodriguezk3@uthscsa.edu

Benjamin Schleif
210-450-1366
schleifb@uthscsa.edu

Morgan Seekatz
210-450-1133
seekatz@uthscsa.edu

Jessica Villarreal

villarreal24@uthscsa.edu

Principal Investigator
Alexander Parikh