Purpose

This study investigates cancer care delivery in adolescent and young adult patients with acute lymphoblastic leukemia. Surveying institutions, evaluating delivery of care at the patient level and seeking input from healthcare providers may help doctors increase rates of adherence to National Comprehensive Cancer Network (NCCN) treatment guidelines. It may also improve care for adolescent and young adult patients with acute lymphoblastic leukemia.

Category

IRB Number
20180072HU
NCT Number
NCT03204916
Sponsor
Children's Oncology Group -



Study Contact

Principal Investigator
Anne-Marie Langevin

Virginia Diaz
210-562-9149
diazvr@uthscsa.edu

Jaclyn Hung
210-450-5358
hungj@uthscsa.edu



Eligibility

Eligible Ages
Between 15 Years and 39 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

    • Newly diagnosed with either Ph- or Ph+ ALL between January 1st, 2012 and December 31st, 2016
    • Both diagnosed and initially treated at the participating National Cancer Institute Community Oncology Research Program (NCORP) institution during induction and post-induction therapy (PIT)

    • Aim 3: Healthcare professional currently employed at a participating NCORP institution

      • Eligible healthcare providers include but are not limited to: physicians, registered nurses (RNs), nurse practitioners, physician assistants, patient advocates, social workers, pharmacists and clinical research associates (CRAs)
    • Aim 3: Direct involvement in the care of AYA ALL patients

Exclusion Criteria

    • Diagnosis of secondary ALL
    • Diagnosis of mixed lineage acute leukemia
    • Diagnosis of acute leukemia of ambiguous lineage (ALAL)
    • Diagnosis of Burkitt's leukemia
    • Transfer of care to another institution during induction or post-induction therapy (PIT)
    • Aim 3: Trainee

Study Design

Study Type
Observational
Observational Model
Case-Only
Time Perspective
Retrospective
Condition
  • Acute Lymphoblastic Leukemia

    • Arm Groups

    ArmDescriptionIntervention

    Observational (cancer care delivery analysis)

    		CHART REVIEW: Patient medical record data is abstracted and treatment plans are reviewed for consistency to NCCN guidelines. For each patient, induction and post-induction care is recorded as either concordant with NCCN guidelines or non-concordant with NCCN guidelines. SITE QUESTIONNAIRE: Participating sites complete a questionnaire which is designed to capture facility-oriented data. FOCUS GROUPS: Healthcare providers participate in focus groups over 2-3 hours to discuss facilitators and barriers to AYA ALL guideline concordance. Participants provide responses which will be recorded on a flip-chart or white board, followed by discussion of the ideas for clarification
  • Other: Medical Chart Review

    Data abstraction and central review

    Other names:

    • Chart Review

  • Behavioral: Discussion

    Participate in focus group

    Other names:

    • Discuss

  • Other: Questionnaire Administration

    Complete questionnaire

    •