Purpose

This phase II trial studies how well multiparametric magnetic resonance imaging (MRI) works in evaluating cancer stage and helping treatment planning in patients with prostate cancer. Multiparametric MRI may be useful for evaluating the type of cancer in finding aggressive disease.

Category

IRB Number
20180668HU
NCT Number
NCT03697148
Open to Enrollment
Yes
Sponsor
ECOG-ACRIN Cancer Research Group -



Study Contact

Principal Investigator
Michael Liss

Frances Crawford
(210) 450-5037
crawfordf1@uthscsa.edu

Sonia Creighton
(210) 450-1366
creighton@uthscsa.edu

Michael Liss
(210) 567-0548
liss@uthscsa.edu

Myrna Montenegro
(210) 450-5954
montenegro@uthscsa.edu

Courtney Nichols
(210) 450-1794
nicholsc2@uthscsa.edu

Mailbox Ctrc Regulatory Affairs
regaffapp@uthscsa.edu

Regulatory Staff
regaffstaff@uthscsa.edu

Kathleen Rodriguez
(210) 450-1365
rodriguezk3@uthscsa.edu

Benjamin Schleif
(210) 450-1366
schleifb@uthscsa.edu

Morgan Seekatz
(210) 450-1133
seekatz@uthscsa.edu



Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
Male
Accepts Healthy Volunteers
No

Inclusion Criteria

    • Recently diagnosed with prostate cancer for whom definitive surgical treatment is indicated

Exclusion Criteria

    • Not suitable to undergo MRI or receive gadolinium-based contrast agent (severe, untreatable claustrophobia; MRI-incompatible metallic objects or implanted medical devices; renal failure; weight greater than allowable by scanner per institutional standard practice)
    • Prior surgical and/or non-surgical treatment for prostate cancer
    • Prior hip replacement or other major pelvic surgery

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Diagnostic
Masking
None (Open Label)
Condition
  • Prostate Carcinoma
  • Arm Groups

    ArmDescriptionIntervention
    Experimental

    Diagnostic (mpMRI)

    Patients undergo mpMRI within 3 months prior to schedule surgery.
  • Diagnostic Test: Multiparametric Magnetic Resonance Imaging

    Undergo mpMRI

    Other names:

    • MP-MRI
    • Multi-parametric MRI
    • Multiparametric MRI