Purpose

To assess the efficacy of ABBV-400 in each solid tumor indication, including advanced or metastatic hepatocellular (HCC), biliary tract cancer (BTC), pancreatic ductal adenocarcinoma (PDAC), esophageal squamous cell carcinoma (ESCC), triple negative (TN) breast cancer (BC), hormone receptor-positive (HR+)/human epidermal growth factor receptor 2 negative (HER2-) BC, and head and neck squamous cell carcinoma (HNSCC). The purpose of this study is to evaluate ABBV-400 in subjects with select solid tumors. This study will consist of multiple cohorts with each cohort investigating ABBV-400 at 3 mg/kg Q3W.

Category

IRB Number
STUDY00000115
NCT Number
-
Open to Enrollment
No
Sponsor
-



Study Contact

Principal Investigator
Daruka Mahadevan

Regulatory Point of Contact
Frances Crawford
210-450-5037
crawfordf1@uthscsa.edu

Regulatory Point of Contact
Myrna Montenegro
210-450-5954
montenegro@uthscsa.edu

Regulatory Point of Contact
Kathleen Rodriguez
210-450-1365
rodriguezk3@uthscsa.edu

Regulatory Point of Contact
Benjamin Schleif
210-450-1366
schleifb@uthscsa.edu

Regulatory Point of Contact
Morgan Seekatz
210-450-1133
seekatz@uthscsa.edu



Eligibility

Eligible Ages
-
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

    Exclusion Criteria