Purpose

This is a Phase Ib, open-label, two-stage study with two active regimens in each stage designed to evaluate the safety and tolerability of combination treatment with atezolizumab, trastuzumab, and pertuzumab (with and without docetaxel) or atezolizumab and trastuzumab emtansine in participants with human epidermal growth factor receptor 2 (HER2) positive metastatic breast cancer (MBC) and locally advanced early breast cancer (EBC), and atezolizumab with doxorubicin and cyclophosphamide in HER2-negative breast cancer.

Category

IRB Number
20150226HU
NCT Number
-
Open to Enrollment
Yes
Sponsor
Hoffmann-La Roche -



Study Contact

Principal Investigator
Marc Feldman

Regulatory Point of Contact
Aleksandra Gruslova
210-567-2244
gruslova@uthscsa.edu



Eligibility

Eligible Ages
18 Years -
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

    Exclusion Criteria