Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation
Lay Description
• To determine the optimal time to initiate anticoagulation with a Non-Vitamin K Oral Anticoagulant (NOAC) after ischemic stroke in patients with non-valvular atrial fibrillation.
Secondary Objectives:
- To compare the rates of primary adverse outcomes in a per protocol analysis
- To compare 30 day clinical outcomes by the modified Rankin scale among the time-to-treatment groups
- To compare 30 day clinical outcomes by the PROMIS-10 scale among the time-to-treatment groups.
- To compare 90 day clinical outcomes by the modified Rankin scale among the time-to-treatment groups
- To explore the optimal timing in subgroups of age, sex, outcome category, and NOAC choice
Category
- Heart, Vascular and Blood
- IRB Number
- 20180802HU
- NCT Number
- ct.gov registration not required
- Open to Enrollment
- Yes
Eligibility
- Eligible Ages
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
Exclusion Criteria
Study Design
Arm Groups
Study Contact
David Pillow
david.pillow@utsa.edu
Donald McGeary
(210) 567-5454
mcgeary@uthscsa.edu
David Pillow
david.pillow@utsa.edu
Principal Investigator
Donald McGeary